CNIH3-AS1

Across TCGA pan-cancer cohorts, CNIH3-AS1 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of CNIH3-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where CNIH3-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CNIH3-AS1 is over-expressed in tumor.

HNSC, LUSC, and LUAD are the cancer types where CNIH3-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CNIH3-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	II,III,IV	+0.147	.011	8	view →
LUSC	Male	All	+0.427	<.001	5	view →
LUAD	Female	All	+0.102	.031	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

CNIH3-AS1–HNSC

Open the HNSC breakdown →