CNBP

Across TCGA patient cohorts, CNBP protein abundance is significantly associated with the RNA expression of many other genes, with 10,152 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CNBP-associated genes across cancer lineages are UMPS, ACAD9, and ALG3. Each is linked with CNBP in more than 4 cancer types. Because this analysis shows association rather than direction, both CNBP-to-partner and partner-to-CNBP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CNBP versus UMPS in LSCC, with a Pearson correlation of 0.66.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNBP→partner) and Y-score (partner→CNBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	UMPS →	+0.706	+0.347	<.001	<.001	3	5
LSCC	ACAD9 →	+0.630	+0.396	<.001	<.001	3	5
UCEC	ALG3 →	+0.661	+0.477	<.001	<.001	3	5
BRCA	RPL32P3 →	+0.452	+0.307	.001	.001	3	4
UCEC	CEP72 →	+0.655	+0.361	.001	.001	3	4
LSCC	SMC4 →	+0.958	+0.428	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,152 associations by consensus.

CNBP vs UMPS — LSCC

Explore this scatter interactively →