CNBD1

Across TCGA patient cohorts, CNBD1 mutation is significantly associated with the RNA expression of many other genes, with 5,002 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CNBD1-associated genes across cancer lineages are RNU7-130P, KLHL3, and CCSAP. Each is linked with CNBD1 in more than 3 cancer types. Because this analysis shows association rather than direction, both CNBD1-to-partner and partner-to-CNBD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU7-130P grouped by CNBD1-low versus CNBD1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNBD1→partner) and Y-score (partner→CNBD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU7-130P →	+0.509	+4.824	<.001	.002	3	4
UCEC	KLHL3 →	-0.611	-2.115	<.001	<.001	3	3
UCEC	CCSAP →	+0.487	+1.606	.003	.003	3	3
UCEC	BUB1B →	+0.792	+1.847	<.001	<.001	3	3
UCEC	PAQR4 →	+0.581	+2.115	.001	<.001	3	3
UCEC	ZNF367 →	+0.807	+2.432	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,002 associations by consensus.

RNU7-130P by CNBD1 expression — COAD

Explore this box plot interactively →