CNBD1

Across TCGA pan-cancer cohorts, CNBD1 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of CNBD1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where CNBD1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CNBD1 is over-expressed in tumor, although a few such as BRCA and COAD show the opposite, repressed pattern.

HNSC, LUSC, and LUAD are the cancer types where CNBD1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CNBD1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	All	+0.051	.001	8	view →
LUSC	All	All	+0.108	.001	4	view →
LUAD	Female	All	+0.032	.009	4	view →
BRCA	All	III,IV	−0.015	.021	2	view →
LIHC	Male	II,III,IV	+0.014	.048	1	view →
COAD	All	All	−0.003	.047	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

CNBD1–HNSC

Open the HNSC breakdown →