CMTR1

Across TCGA patient cohorts, CMTR1 mutation is significantly associated with the RNA expression of many other genes, with 4,048 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CMTR1-associated genes across cancer lineages are RN7SL763P, CYCSP48, and RPS27P5. Each is linked with CMTR1 in more than 2 cancer types. Because this analysis shows association rather than direction, both CMTR1-to-partner and partner-to-CMTR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL763P grouped by CMTR1-low versus CMTR1-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CMTR1→partner) and Y-score (partner→CMTR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	RN7SL763P →	+0.138	+5.187	<.001	.007	3	3
BLCA	CYCSP48 →	+0.186	+5.018	<.001	.004	3	2
BLCA	RPS27P5 →	+0.230	+6.484	<.001	<.001	3	2
READ	ZNF90P2 →	+0.044	+5.925	<.001	.002	3	2
UCEC	SLC7A11 →	+0.976	+2.818	<.001	.001	3	2
UCEC	TMEM263 →	+0.515	+2.510	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,048 associations by consensus.

RN7SL763P by CMTR1 expression — STAD

Explore this box plot interactively →