CMTR1

Across TCGA pan-cancer cohorts, CMTR1 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated CMTR1 data layer compared with 4 for mutation status and 7 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher CMTR1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated CMTR1 expression acts as an unfavorable survival marker, although some lineages such as KIRC and READ show a favorable association.

KIRC, READ, and COAD are the cancer types where CMTR1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.740	0.520	.001	59	view →
READ	OS	Quartile	All	1.000	0.252	<.001	53	view →
COAD	DFS	Median	II,III,IV	0.586	0.724	.004	38	view →
UCEC	DFS	Quartile	All	0.531	0.814	<.001	36	view →
KICH	OS	Quartile	All	0.537	1.000	.002	29	view →
SCLC	DFS	Tertile	II,III,IV	0.612	0.224	.001	26	view →
UCS	OS	Median	II,III,IV	0.604	0.245	.010	18	view →
BRCA	DFS	Tertile	III,IV	0.933	0.819	.009	18	view →
LIHC	DFS	Tertile	All	0.457	0.615	.002	18	view →
LUSC	DFS	Quartile	III,IV	0.382	0.935	.008	14	view →
PAAD	OS	Tertile	All	0.518	0.250	.009	13	view →
ACC	DFS	Median	All	0.323	0.587	.010	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

CMTR1–KIRC (DFS)

Open the KIRC breakdown →