CMTM8

Across TCGA patient cohorts, CMTM8 mutation is significantly associated with the RNA expression of many other genes, with 957 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CMTM8-associated genes across cancer lineages are RNA5SP422, EIF4EBP1P1, and GLTPP1. Each is linked with CMTM8 in more than 1 cancer types. Because this analysis shows association rather than direction, both CMTM8-to-partner and partner-to-CMTM8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP422 grouped by CMTM8-low versus CMTM8-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CMTM8→partner) and Y-score (partner→CMTM8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP422 →	+0.743	+2.448	.001	.004	3	2
UCEC	EIF4EBP1P1 →	+0.302	+2.448	.005	.002	3	2
COAD	GLTPP1 →	+0.098	+5.790	.001	.003	3	2
UCEC	PGAP2 →	+0.458	+3.595	.008	.001	3	1
UCEC	NOCT →	+1.129	+3.595	<.001	.001	3	1
UCEC	VPS26B →	+0.516	+3.606	.002	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 957 associations by consensus.

RNA5SP422 by CMTM8 expression — UCEC

Explore this box plot interactively →