glycolipid transfer protein pseudogene 1Genealiases: []
Q-omics provides the consensus-scored GLTPP1 profile across patient tissues and cancer cell-line models. GLTPP1 expression is associated with patient survival in 12 of 34 cancer types, with the highest sampling consensus in KIRP. Among the 18 cancer types available for tumor–normal comparison, GLTPP1 is differentially expressed in 3, with the highest sampling consensus in PAAD. Additionally, GLTPP1 RNA expression shows 4,958 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight KIRP, PAAD, and STAD as cancer lineages where GLTPP1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for GLTPP1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes GLTPP1 survival associations across molecular data types. GLTPP1 RNA expression shows survival associations in the most cancer types (12). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible GLTPP1 RNA expression–survival associations across cancer types. High GLTPP1 expression shows unfavorable associations in KIRP, THCA, UCEC, PAAD and ACC, but favorable associations in ESCA. The KIRP Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .004). Together, the overview and detailed table identify KIRP as the clearest survival context for GLTPP1 RNA expression.
This table summarizes GLTPP1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 3. The strongest signals are observed in PAAD for RNA.
This table ranks reproducible tumor–normal expression differences for GLTPP1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. GLTPP1 shows lower tumor expression in PAAD and KIRP and higher tumor expression in LUSC. The PAAD box plot shows higher GLTPP1 RNA expression in normal versus tumor tissue (log2 FC = −0.155, t-test p = .047).
This table shows molecular features associated with GLTPP1 in patient tissues and cancer cell lines. In patient samples, GLTPP1 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.
