CMPK2

Across TCGA cell cohorts, CMPK2 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. CNS shows the largest number of these associations.

The most reproducible CMPK2-associated genes across cancer lineages are SPAM1, OPN1MW2, and GPRC6A. Each is linked with CMPK2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CMPK2-to-partner and partner-to-CMPK2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SPAM1 grouped by CMPK2-low versus CMPK2-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CMPK2→partner) and Y-score (partner→CMPK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	SPAM1 →	+0.004	+4.321	<.001	.009	3	1
CNS	OPN1MW2 →	+0.011	+4.754	.009	.005	3	1
CNS	GPRC6A →	+0.020	+4.169	<.001	.008	3	1
CNS	C10orf53 →	+0.083	+5.044	<.001	.001	3	1
CNS	PLA2G2C →	+0.004	+4.754	<.001	.005	3	1
CNS	VN1R2 →	+0.035	+4.643	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

SPAM1 by CMPK2 expression — CNS

Explore this box plot interactively →