CMA1

Across TCGA patient cohorts, CMA1 mutation is significantly associated with the RNA expression of many other genes, with 761 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CMA1-associated genes across cancer lineages are MYO19, RN7SL147P, and TADA3. Each is linked with CMA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CMA1-to-partner and partner-to-CMA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYO19 grouped by CMA1-low versus CMA1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CMA1→partner) and Y-score (partner→CMA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MYO19 →	+0.620	+3.609	.001	.001	3	2
UCEC	RN7SL147P →	+0.175	+2.398	.002	.004	3	2
SKCM	TADA3 →	+0.426	+2.555	.007	.009	3	2
SKCM	EMC3-AS1 →	+0.550	+3.604	.003	.001	3	2
SKCM	RNA5SP93 →	+0.084	+4.769	<.001	.002	3	2
SKCM	RNU6-1292P →	+0.133	+3.732	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 761 associations by consensus.

MYO19 by CMA1 expression — UCEC

Explore this box plot interactively →