CMA1

Across TCGA pan-cancer cohorts, CMA1 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of CMA1’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where CMA1 RNA is repressed in tumor relative to normal tissue. In most cancer types CMA1 is over-expressed in tumor, although a few such as BLCA and COAD show the opposite, repressed pattern.

BLCA, COAD, and KICH are the cancer types where CMA1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CMA1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	Male	III,IV	−3.884	<.001	11	view →
COAD	All	IV	−2.538	<.001	11	view →
KICH	All	All	−0.459	<.001	9	view →
HNSC	Male	IV	−2.033	<.001	8	view →
STAD	All	III,IV	−1.745	<.001	8	view →
LUAD	All	II,III,IV	−1.055	<.001	8	view →
READ	All	II,III,IV	−2.967	<.001	7	view →
LUSC	Male	II,III,IV	−1.390	<.001	7	view →
BRCA	All	III,IV	−2.524	<.001	6	view →
UCEC	All	All	−1.541	<.001	6	view →
PRAD	All	All	−0.496	.002	2	view →
CHOL	All	All	−0.357	.031	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

CMA1–BLCA

Open the BLCA breakdown →