CLUH

Across TCGA patient cohorts, CLUH RNA expression is significantly associated with the RNA expression of many other genes, with 18,073 significant associations in total. ACC shows the largest number of these associations.

The most reproducible CLUH-associated genes across cancer lineages are SCO1, NEURL4, and NDUFS2. Each is linked with CLUH in more than 32 cancer types. Because this analysis shows association rather than direction, both CLUH-to-partner and partner-to-CLUH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CLUH versus SCO1 in ACC, with a Pearson correlation of 0.83.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLUH→partner) and Y-score (partner→CLUH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ACC	SCO1 →	+0.870	+0.917	<.001	<.001	3	33
SCLC	NEURL4 →	+0.921	+0.979	<.001	<.001	3	33
ACC	NDUFS2 →	+1.029	+1.065	<.001	<.001	3	33
ACC	CS →	+1.142	+0.950	<.001	<.001	3	33
CHOL	COX10 →	+1.007	+1.094	<.001	<.001	3	33
DLBC	TRAP1 →	+1.218	+0.808	<.001	<.001	3	33

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,073 associations by consensus.

CLUH vs SCO1 — ACC

Explore this scatter interactively →