CLUH

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CLUH RNA expression is significantly associated with the protein abundance of many other proteins, with 14,675 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CLUH-associated proteins across cancer lineages are CLUH_S664, ELAC2, and SNRNP200. Each is linked with CLUH in more than 5 cancer types. Because this analysis shows association rather than direction, both CLUH-to-partner and partner-to-CLUH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CLUH versus CLUH_S664 in LSCC, with a Pearson correlation of 0.51.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CLUH→partner) and Y-score (partner→CLUH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCCLUH_S664 →+0.530+0.513<.001<.00136
LSCCELAC2 →+0.360+0.690<.001<.00136
BRCASNRNP200 →+0.217+0.558<.001.00635
BRCABCCIP →+0.339+0.547<.001.00335
BRCAORC3 →+0.303+0.683<.001.00335
LSCCUSP39 →+0.293+0.543<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 14,675 associations by consensus.

CLUH vs CLUH_S664 — LSCC

Per-sample scatter of CLUH vs CLUH_S664 in LSCC (Pearson r = 0.51).

Explore this scatter interactively →

Exploration