CLUH

Across TCGA cell cohorts, CLUH RNA expression is significantly associated with the go_rna of many other GO terms, with 5,068 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CLUH-associated GO terms across cancer lineages are Ribosomal large subunit assembly, rRNA modification, and Mitochondrial ribosome assembly. Each is linked with CLUH in more than 18 cancer types. Because this analysis shows association rather than direction, both CLUH-to-partner and partner-to-CLUH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ribosomal large subunit assembly grouped by CLUH-low versus CLUH-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CLUH→partner) and Y-score (partner→CLUH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Ribosomal large subunit assembly →	+0.179	+1.335	<.001	.002	3	19
LUNG_SCLC	rRNA modification →	+0.121	+1.097	<.001	<.001	3	18
LUNG_SCLC	Mitochondrial ribosome assembly →	+0.110	+0.888	<.001	<.001	3	18
URINARY_TRACT	IMP biosynthetic process →	+0.215	+1.127	<.001	<.001	3	18
BONE	Ribosome assembly →	+0.135	+1.591	<.001	<.001	3	18
BLOOD_Myeloma	Mitochondrial large ribosomal subunit assembly →	+0.176	+1.341	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,068 associations by consensus.

Ribosomal large subunit assembly by CLUH expression — BONE

Explore this box plot interactively →