CLSTN1

Across TCGA patient cohorts, CLSTN1 mutation is significantly associated with the RNA expression of many other genes, with 5,132 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CLSTN1-associated genes across cancer lineages are GOT1, PINCR, and SPTY2D1. Each is linked with CLSTN1 in more than 2 cancer types. Because this analysis shows association rather than direction, both CLSTN1-to-partner and partner-to-CLSTN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GOT1 grouped by CLSTN1-low versus CLSTN1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLSTN1→partner) and Y-score (partner→CLSTN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	GOT1 →	+0.516	+2.834	<.001	.001	3	3
UCEC	PINCR →	+0.169	+1.542	<.001	<.001	3	3
UCEC	SPTY2D1 →	+0.434	+2.040	<.001	<.001	3	2
UCEC	GEMIN4 →	+0.521	+1.765	<.001	<.001	3	2
UCEC	AKAP5 →	+0.478	+2.949	<.001	<.001	3	2
UCEC	ZNF771 →	+0.279	+1.415	.007	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,132 associations by consensus.

GOT1 by CLSTN1 expression — COAD

Explore this box plot interactively →