CLSPN

Across TCGA patient cohorts, CLSPN RNA expression is significantly associated with the protein abundance of many other proteins, with 23,378 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CLSPN-associated proteins across cancer lineages are RFC2, RPL12_S38, and RRM2. Each is linked with CLSPN in more than 9 cancer types. Because this analysis shows association rather than direction, both CLSPN-to-partner and partner-to-CLSPN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CLSPN versus RFC2 in LSCC, with a Pearson correlation of 0.66.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CLSPN→partner) and Y-score (partner→CLSPN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RFC2 →	+0.447	+0.753	<.001	<.001	3	10
LUAD	RPL12_S38 →	+1.336	+1.149	<.001	<.001	3	10
LUAD	RRM2 →	+1.027	+1.188	<.001	<.001	3	10
GBM	SMC2 →	+0.827	+1.089	<.001	<.001	3	10
GBM	SMC4 →	+0.785	+1.064	<.001	<.001	3	10
OV	KPNA2 →	+0.855	+1.230	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 23,378 associations by consensus.

CLSPN vs RFC2 — LSCC

Explore this scatter interactively →