CLEC4GP1

Across TCGA patient cohorts, CLEC4GP1 mutation is significantly associated with the RNA expression of many other genes, with 331 significant associations in total. COAD shows the largest number of these associations.

The most reproducible CLEC4GP1-associated genes across cancer lineages are RNU6-839P, RAC1P6, and RNU6-735P. Each is linked with CLEC4GP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CLEC4GP1-to-partner and partner-to-CLEC4GP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-839P grouped by CLEC4GP1-low versus CLEC4GP1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLEC4GP1→partner) and Y-score (partner→CLEC4GP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU6-839P →	+0.458	+7.816	<.001	.008	3	2
SKCM	RAC1P6 →	+0.074	+7.816	<.001	.008	3	2
COAD	RNU6-735P →	+1.348	+7.741	<.001	.009	3	2
COAD	RNU6-1241P →	+0.753	+7.741	<.001	.009	3	2
COAD	OR4A45P →	+0.364	+7.741	<.001	.009	3	2
COAD	RPS28P8 →	+0.763	+7.741	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 331 associations by consensus.

RNU6-839P by CLEC4GP1 expression — SKCM

Explore this box plot interactively →