CLEC18B

Across TCGA cell cohorts, CLEC18B mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CLEC18B-associated genes across cancer lineages are ACER1, OR2C1, and H1-6. Each is linked with CLEC18B in more than 1 cancer types. Because this analysis shows association rather than direction, both CLEC18B-to-partner and partner-to-CLEC18B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACER1 grouped by CLEC18B-low versus CLEC18B-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLEC18B→partner) and Y-score (partner→CLEC18B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ACER1 →	+0.085	+4.145	.002	.001	3	1
LARGE_INTESTINE	OR2C1 →	+0.105	+3.578	.001	.006	3	1
LARGE_INTESTINE	H1-6 →	+0.117	+3.509	<.001	.008	3	1
LARGE_INTESTINE	ADAM7 →	+0.004	+3.345	<.001	.007	3	1
LUNG_SCLC	MAGEB3 →	+0.150	+4.044	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

ACER1 by CLEC18B expression — LARGE_INTESTINE

Explore this box plot interactively →