CLEC18B

Across TCGA pan-cancer cohorts, CLEC18B RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated CLEC18B data layer compared with 6 for mutation status and 1 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher CLEC18B RNA is associated with better overall survival. In most high-consensus cancer types, elevated CLEC18B expression acts as an unfavorable survival marker, although some lineages such as KIRC and SCLC show a favorable association.

KIRC, LGG, and SCLC are the cancer types where CLEC18B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.708	0.547	<.001	62	view →
LGG	DFS	Median	All	0.252	0.521	<.001	54	view →
SCLC	OS	Quartile	II,III,IV	0.885	0.345	<.001	40	view →
BLCA	OS	Quartile	III,IV	0.791	0.563	.001	35	view →
GBM	OS	Median	All	0.215	0.312	.005	29	view →
THYM	DFS	Median	II,III,IV	0.948	0.493	.002	19	view →
KIRP	DFS	Tertile	II,III,IV	0.838	0.530	.006	19	view →
COAD	OS	Tertile	All	0.714	0.906	.001	18	view →
THCA	OS	Median	All	0.960	1.000	.006	17	view →
ACC	OS	Quartile	All	0.784	0.974	.009	16	view →
PRAD	DFS	Tertile	All	0.692	0.897	.003	14	view →
LIHC	OS	Quartile	III,IV	0.178	0.539	.010	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

CLEC18B–KIRC (OS)

Open the KIRC breakdown →