CLDND2

Across TCGA patient cohorts, CLDND2 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,148 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible CLDND2-associated GO terms across cancer lineages are Oxidative phosphorylation, Proton motive force-driven ATP synthesis, and Methylglyoxal metabolic process. Each is linked with CLDND2 in more than 24 cancer types. Because this analysis shows association rather than direction, both CLDND2-to-partner and partner-to-CLDND2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Oxidative phosphorylation grouped by CLDND2-low versus CLDND2-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CLDND2→partner) and Y-score (partner→CLDND2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Oxidative phosphorylation →	+0.067	+0.581	.004	<.001	2	25
ESCA	Proton motive force-driven ATP synthesis →	+0.057	+0.527	.003	<.001	3	23
KIRC	Methylglyoxal metabolic process →	+0.050	+0.515	<.001	<.001	3	23
HNSC	NADH dehydrogenase complex assembly →	+0.044	+0.555	<.001	<.001	3	22
MESO	Regulation of electron transfer activity →	+0.049	+0.765	<.001	<.001	3	22
ACC	Regulation of cytochrome-c oxidase activity →	+0.047	+0.928	<.001	<.001	2	23

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,148 associations by consensus.

Oxidative phosphorylation by CLDND2 expression — ESCA

Explore this box plot interactively →