CLDND2

Across TCGA cell cohorts, CLDND2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,982 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CLDND2-associated GO terms across cancer lineages are Cellular detoxification of aldehyde, Short-chain fatty acid metabolic process, and IMP salvage. Each is linked with CLDND2 in more than 7 cancer types. Because this analysis shows association rather than direction, both CLDND2-to-partner and partner-to-CLDND2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular detoxification of aldehyde grouped by CLDND2-low versus CLDND2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CLDND2→partner) and Y-score (partner→CLDND2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Cellular detoxification of aldehyde →	+0.120	+0.545	.004	.009	3	8
LARGE_INTESTINE	Short-chain fatty acid metabolic process →	+0.110	+0.629	.007	.001	2	8
OESOPHAGUS	IMP salvage →	+0.214	+1.040	.001	.002	3	7
LUNG_NSCLC_LUAD	Cellular detoxification →	+0.073	+0.510	<.001	<.001	3	7
LARGE_INTESTINE	Retinal metabolic process →	+0.137	+0.631	<.001	<.001	3	6
LUNG_NSCLC_LUAD	Fatty acid catabolic process →	+0.058	+0.548	<.001	.008	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,982 associations by consensus.

Cellular detoxification of aldehyde by CLDND2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →