CLDN23

Across TCGA patient cohorts, CLDN23 RNA expression is significantly associated with the RNA expression of many other genes, with 17,803 significant associations in total. THYM shows the largest number of these associations.

The most reproducible CLDN23-associated genes across cancer lineages are UNC93B1, SH2D4A, and ARSD. Each is linked with CLDN23 in more than 25 cancer types. Because this analysis shows association rather than direction, both CLDN23-to-partner and partner-to-CLDN23 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CLDN23 versus UNC93B1 in LGG, with a Pearson correlation of 0.72.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLDN23→partner) and Y-score (partner→CLDN23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LGG	UNC93B1 →	+1.223	+0.578	<.001	<.001	3	26
SCLC	SH2D4A →	+1.294	+1.094	.004	<.001	2	26
SCLC	ARSD →	+2.191	+1.339	<.001	<.001	2	26
UCS	TNFRSF10A →	+1.594	+1.404	<.001	.001	3	25
LUAD	RBPMS-AS1 →	+0.742	+0.682	<.001	<.001	3	24
SCLC	CXCL16 →	+1.598	+1.019	<.001	<.001	3	24

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,803 associations by consensus.

CLDN23 vs UNC93B1 — LGG

Explore this scatter interactively →