CLDN15

Across TCGA patient cohorts, CLDN15 protein abundance is significantly associated with the RNA expression of many other genes, with 1,690 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CLDN15-associated genes across cancer lineages are YPEL1, LTBR, and PLSCR4. Each is linked with CLDN15 in more than 1 cancer types. Because this analysis shows association rather than direction, both CLDN15-to-partner and partner-to-CLDN15 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CLDN15 versus YPEL1 in HNSC, with a Pearson correlation of -0.81.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLDN15→partner) and Y-score (partner→CLDN15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	YPEL1 →	-1.353	-1.583	.001	.009	3	1
HNSC	LTBR →	-0.616	-1.062	.005	.007	3	1
HNSC	PLSCR4 →	+0.919	+1.062	.005	.007	3	1
HNSC	KCNK15 →	+0.891	+1.062	<.001	.007	3	1
HNSC	ASS1 →	+2.508	+1.062	.003	.007	3	1
HNSC	FAM189A2 →	-1.783	-1.583	.009	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,690 associations by consensus.

CLDN15 vs YPEL1 — HNSC

Explore this scatter interactively →