CLCA4-AS1

Across TCGA patient cohorts, CLCA4-AS1 mutation is significantly associated with the RNA expression of many other genes, with 3,166 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CLCA4-AS1-associated genes across cancer lineages are CREB3L2, SRPRA, and ADRA2C. Each is linked with CLCA4-AS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CLCA4-AS1-to-partner and partner-to-CLCA4-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CREB3L2 grouped by CLCA4-AS1-low versus CLCA4-AS1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLCA4-AS1→partner) and Y-score (partner→CLCA4-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CREB3L2 →	+0.472	+1.447	.001	.006	3	2
UCEC	SRPRA →	+0.404	+1.893	<.001	<.001	3	2
UCEC	ADRA2C →	-0.977	-2.000	<.001	.008	3	2
UCEC	FAM118B →	+0.612	+3.386	<.001	<.001	3	2
UCEC	GFPT1 →	+0.567	+2.436	<.001	.001	3	2
UCEC	RNU1-17P →	+0.166	+2.042	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,166 associations by consensus.

CREB3L2 by CLCA4-AS1 expression — UCEC

Explore this box plot interactively →