CLCA4-AS1

Across TCGA pan-cancer cohorts, CLCA4-AS1 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated CLCA4-AS1 data layer compared with 6 for mutation status.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher CLCA4-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CLCA4-AS1 expression acts as an unfavorable survival marker, although some lineages such as BLCA and COAD show a favorable association.

KIRC, BLCA, and LAML are the cancer types where CLCA4-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	IV	0.335	0.719	<.001	65	view →
BLCA	OS	Median	II,III,IV	0.667	0.542	.002	41	view →
LAML	DFS	Quartile	All	0.221	0.701	<.001	30	view →
OV	OS	Median	IV	0.600	0.889	.004	22	view →
COAD	DFS	Tertile	All	0.749	0.594	.002	21	view →
KIRP	OS	Tertile	II,III,IV	0.961	0.776	.029	17	view →
STAD	OS	Median	IV	0.183	0.509	.021	15	view →
READ	OS	Median	All	0.819	0.970	.011	9	view →
DLBC	DFS	Median	IV	0.195	0.923	.038	7	view →
HNSC	OS	Median	All	0.799	0.702	.007	7	view →
LIHC	OS	Tertile	All	0.934	0.738	.041	6	view →
ESCA	DFS	Median	All	0.912	0.562	.037	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

CLCA4-AS1–KIRC (DFS)

Open the KIRC breakdown →