CLASRP

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CLASRP protein abundance is significantly associated with the RNA expression of many other genes, with 12,864 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CLASRP-associated genes across cancer lineages are MBTD1, MCM3AP-AS1, and GAS5. Each is linked with CLASRP in more than 4 cancer types. Because this analysis shows association rather than direction, both CLASRP-to-partner and partner-to-CLASRP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CLASRP versus MBTD1 in LSCC, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLASRP→partner) and Y-score (partner→CLASRP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCMBTD1 →+0.642+0.219<.001<.00135
GBMMCM3AP-AS1 →+0.445+0.364<.001<.00135
LSCCGAS5 →+0.626+0.212<.001<.00135
HNSCC1orf112 →+0.791+0.256.001<.00135
UCECCENPL →+0.690+0.277<.001<.00135
GBMRAD18 →+0.624+0.400.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 12,864 associations by consensus.

CLASRP vs MBTD1 — LSCC

Per-sample scatter of CLASRP vs MBTD1 in LSCC (Pearson r = 0.42).

Explore this scatter interactively →

Exploration