CLASRP

Across TCGA pan-cancer cohorts, CLASRP RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of CLASRP’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where CLASRP RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CLASRP is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

KIRC, COAD, and LIHC are the cancer types where CLASRP tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CLASRP RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	IV	+0.884	<.001	11	view →
COAD	Male	IV	+1.048	<.001	10	view →
LIHC	Female	II,III,IV	+1.253	<.001	8	view →
HNSC	Male	III,IV	+0.658	<.001	8	view →
KIRP	All	III,IV	+0.604	.012	5	view →
STAD	All	II,III,IV	+0.597	.001	5	view →
READ	All	All	+0.695	<.001	4	view →
CHOL	All	All	+1.666	<.001	3	view →
ESCA	All	All	+0.567	.002	3	view →
LUAD	All	All	+0.272	.014	3	view →
KICH	All	All	−0.467	.006	2	view →
LUSC	Male	All	+0.464	.003	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

CLASRP–KIRC

Open the KIRC breakdown →