CLASRP

Across TCGA pan-cancer cohorts, CLASRP RNA is linked to patient survival in 28 of 34 cancer types, making it the most broadly survival-associated CLASRP data layer compared with 3 for mutation status and 5 for mass-spec protein.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher CLASRP RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CLASRP expression acts as an unfavorable survival marker, although some lineages such as BLCA and THYM show a favorable association.

ACC, BLCA, and KIRC are the cancer types where CLASRP RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.342	0.823	<.001	133	view →
BLCA	OS	Tertile	All	0.684	0.508	<.001	104	view →
KIRC	DFS	Quartile	All	0.447	0.683	<.001	99	view →
COAD	OS	Tertile	All	0.775	0.930	.001	53	view →
UVM	DFS	Median	III,IV	0.191	1.000	<.001	43	view →
LIHC	DFS	Tertile	All	0.423	0.595	<.001	40	view →
PRAD	DFS	Median	All	0.651	0.931	<.001	32	view →
THYM	DFS	Quartile	All	0.835	0.480	.003	30	view →
LGG	DFS	Median	All	0.645	0.820	<.001	28	view →
KICH	DFS	Tertile	III,IV	0.169	0.766	.003	19	view →
SKCM	DFS	Quartile	III,IV	0.123	0.482	<.001	18	view →
HNSC	OS	Median	All	0.788	0.713	.018	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 28 lineages.

CLASRP–ACC (DFS)

Open the ACC breakdown →