CLASRP

Across TCGA patient cohorts, CLASRP mutation is significantly associated with the RNA expression of many other genes, with 3,268 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CLASRP-associated genes across cancer lineages are RNU6-468P, RNA5SP120, and MTCO2P23. Each is linked with CLASRP in more than 1 cancer types. Because this analysis shows association rather than direction, both CLASRP-to-partner and partner-to-CLASRP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-468P grouped by CLASRP-low versus CLASRP-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLASRP→partner) and Y-score (partner→CLASRP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-468P →	+0.215	+4.821	<.001	.003	3	2
LUAD	RNA5SP120 →	+0.361	+4.859	<.001	.004	3	2
LUAD	MTCO2P23 →	+0.034	+4.612	<.001	.006	3	2
HNSC	MIR4757 →	+0.285	+4.526	<.001	.007	3	2
CESC	RN7SKP263 →	+0.098	+4.984	<.001	.003	3	2
SKCM	RNU6-514P →	+0.281	+3.508	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,268 associations by consensus.

RNU6-468P by CLASRP expression — COAD

Explore this box plot interactively →