CLASRP

Across TCGA patient cohorts, CLASRP mutation is significantly associated with the total protein of many other genes, with 10 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CLASRP-associated genes across cancer lineages are eEF2, INPP4B, and mTOR_pS2448. Each is linked with CLASRP in more than 1 cancer types. Because this analysis shows association rather than direction, both CLASRP-to-partner and partner-to-CLASRP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by CLASRP-low versus CLASRP-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLASRP→partner) and Y-score (partner→CLASRP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.364	+1.906	.011	.016	3	1
UCEC	INPP4B →	-0.281	-3.169	.030	.018	3	1
UCEC	mTOR_pS2448 →	-0.148	-2.095	.013	.017	3	1
UCEC	Annexin-1 →	+0.537	+2.999	.011	.035	3	1
UCEC	VHL →	-0.682	-2.115	.012	.017	3	1
UCEC	ATM →	-0.487	-2.308	.007	.033	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

eEF2 by CLASRP expression — UCEC

Explore this box plot interactively →