CLASRP

Across TCGA cell cohorts, CLASRP RNA expression is significantly associated with the go_rna of many other GO terms, with 4,324 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CLASRP-associated GO terms across cancer lineages are Regulation of mRNA splicing, via spliceosome, mRNA splice site recognition, and Subtelomeric heterochromatin formation. Each is linked with CLASRP in more than 17 cancer types. Because this analysis shows association rather than direction, both CLASRP-to-partner and partner-to-CLASRP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mRNA splicing, via spliceosome grouped by CLASRP-low versus CLASRP-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CLASRP→partner) and Y-score (partner→CLASRP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Regulation of mRNA splicing, via spliceosome →	+0.113	+0.919	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	mRNA splice site recognition →	+0.154	+0.876	.001	.001	3	17
SOFT_TISSUE	Subtelomeric heterochromatin formation →	+0.117	+0.848	<.001	<.001	3	17
BONE	Late viral transcription →	+0.124	+0.972	<.001	<.001	3	17
LUNG_SCLC	Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway →	+0.132	+0.765	<.001	<.001	3	16
LUNG_SCLC	Regulation of RNA splicing →	+0.080	+0.722	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,324 associations by consensus.

Regulation of mRNA splicing, via spliceosome by CLASRP expression — SOFT_TISSUE

Explore this box plot interactively →