CKMT1B

Across TCGA patient cohorts, CKMT1B mutation is significantly associated with the RNA expression of many other genes, with 738 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CKMT1B-associated genes across cancer lineages are MIR320B1, LINC02438, and NES. Each is linked with CKMT1B in more than 1 cancer types. Because this analysis shows association rather than direction, both CKMT1B-to-partner and partner-to-CKMT1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR320B1 grouped by CKMT1B-low versus CKMT1B-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CKMT1B→partner) and Y-score (partner→CKMT1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MIR320B1 →	+0.271	+2.705	.001	.008	3	2
UCEC	LINC02438 →	+0.683	+3.346	.001	.005	3	2
SKCM	NES →	+1.500	+3.195	.004	.009	3	2
BRCA	MIR6082 →	+0.186	+7.471	<.001	.008	3	1
HNSC	USP9YP22 →	+0.089	+7.954	<.001	.008	3	1
BRCA	RN7SKP209 →	+0.251	+5.409	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 738 associations by consensus.

MIR320B1 by CKMT1B expression — SKCM

Explore this box plot interactively →