CKMT1B

Across TCGA pan-cancer cohorts, CKMT1B RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated CKMT1B data layer compared with 2 for mutation status.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher CKMT1B RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated CKMT1B expression acts as an unfavorable survival marker, although some lineages such as KIRP and LGG show a favorable association.

KIRP, UCEC, and LGG are the cancer types where CKMT1B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Median	All	0.966	0.850	<.001	119	view →
UCEC	OS	Quartile	All	0.537	0.879	<.001	100	view →
LGG	OS	Median	All	0.525	0.378	<.001	42	view →
UCS	DFS	Median	IV	0.367	0.952	.001	40	view →
LUSC	OS	Quartile	All	0.510	0.348	.005	36	view →
MESO	DFS	Quartile	All	0.474	0.283	.017	34	view →
CESC	DFS	Median	All	0.820	0.654	.001	32	view →
ESCA	OS	Median	II,III,IV	0.449	0.645	.014	23	view →
LUAD	OS	Tertile	III,IV	0.567	0.797	.005	19	view →
COAD	OS	Tertile	III,IV	0.647	0.915	.005	16	view →
THCA	DFS	Quartile	All	0.880	0.968	.024	14	view →
DLBC	DFS	Median	III,IV	0.196	0.862	.008	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

CKMT1B–KIRP (DFS)

Open the KIRP breakdown →