CKMT1B

Across TCGA cell cohorts, CKMT1B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,216 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CKMT1B-associated GO terms across cancer lineages are Peptidyl-lysine oxidation, PML body organization, and Establishment of epithelial cell apical/basal polarity. Each is linked with CKMT1B in more than 11 cancer types. Because this analysis shows association rather than direction, both CKMT1B-to-partner and partner-to-CKMT1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peptidyl-lysine oxidation grouped by CKMT1B-low versus CKMT1B-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CKMT1B→partner) and Y-score (partner→CKMT1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Peptidyl-lysine oxidation →	-2.050	-3.785	<.001	<.001	3	12
LUNG_NSCLC_LUSC	PML body organization →	-0.304	-3.324	<.001	.001	3	11
LUNG_NSCLC_LUSC	Establishment of epithelial cell apical/basal polarity →	-0.303	-3.335	<.001	<.001	3	11
BREAST	Cell adhesion mediated by integrin →	-0.154	-2.075	.001	<.001	3	10
LUNG_NSCLC_LUSC	Regulation of white fat cell proliferation →	-0.394	-3.471	<.001	<.001	3	10
SOFT_TISSUE	Protein activation cascade →	-0.329	-1.777	<.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,216 associations by consensus.

Peptidyl-lysine oxidation by CKMT1B expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →