CKMT1B

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CKMT1B protein abundance is significantly associated with the go_rna of many other GO terms, with 1,743 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible CKMT1B-associated GO terms across cancer lineages are Phosphagen biosynthetic process, Phosphocreatine biosynthetic process, and Phosphocreatine metabolic process. Each is linked with CKMT1B in more than 7 cancer types. Because this analysis shows association rather than direction, both CKMT1B-to-partner and partner-to-CKMT1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Phosphagen biosynthetic process grouped by CKMT1B-low versus CKMT1B-high in URINARY_TRACT.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CKMT1B→partner) and Y-score (partner→CKMT1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
URINARY_TRACTPhosphagen biosynthetic process →+0.511+4.150.007.00828
URINARY_TRACTPhosphocreatine biosynthetic process →+0.511+4.150.007.00828
URINARY_TRACTPhosphocreatine metabolic process →+0.511+4.150.007.00828
BREASTRegulation of natural killer cell activation →-0.188-2.126.001<.00136
CNSSubstrate adhesion-dependent cell spreading →-0.184-2.394.003.00236
BREASTCentral nervous system projection neuron axonogenesis →+0.133+3.723.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,743 associations by consensus.

Phosphagen biosynthetic process by CKMT1B expression — URINARY_TRACT

Box plot of Phosphagen biosynthetic process in CKMT1B-low vs CKMT1B-high samples in URINARY_TRACT.

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Exploration