CKLF-CMTM1

Across TCGA patient cohorts, CKLF-CMTM1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,160 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible CKLF-CMTM1-associated GO terms across cancer lineages are Microtubule organizing center localization, Protein localization to microtubule organizing center, and Maintenance of cell number. Each is linked with CKLF-CMTM1 in more than 31 cancer types. Because this analysis shows association rather than direction, both CKLF-CMTM1-to-partner and partner-to-CKLF-CMTM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule organizing center localization grouped by CKLF-CMTM1-low versus CKLF-CMTM1-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CKLF-CMTM1→partner) and Y-score (partner→CKLF-CMTM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	Microtubule organizing center localization →	+0.079	+0.523	<.001	<.001	3	32
DLBC	Protein localization to microtubule organizing center →	+0.062	+0.475	.003	<.001	2	32
ESCA	Maintenance of cell number →	+0.049	+0.374	.003	<.001	3	31
DLBC	Centriole elongation →	+0.083	+0.501	<.001	<.001	3	31
ESCA	Cytoskeleton-dependent cytokinesis →	+0.059	+0.413	<.001	<.001	3	31
ESCA	Cytokinesis →	+0.075	+0.520	<.001	<.001	3	31

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,160 associations by consensus.

Microtubule organizing center localization by CKLF-CMTM1 expression — DLBC

Explore this box plot interactively →