CISD2

Across TCGA patient cohorts, CISD2 protein abundance is significantly associated with the RNA expression of many other genes, with 11,247 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible CISD2-associated genes across cancer lineages are TNXB, SPARCL1, and CHRDL1. Each is linked with CISD2 in more than 5 cancer types. Because this analysis shows association rather than direction, both CISD2-to-partner and partner-to-CISD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CISD2 versus TNXB in UCEC, with a Pearson correlation of -0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CISD2→partner) and Y-score (partner→CISD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TNXB →	-1.068	-0.429	<.001	.001	3	6
UCEC	SPARCL1 →	-1.356	-0.458	<.001	<.001	3	5
UCEC	CHRDL1 →	-1.459	-0.445	<.001	<.001	3	4
LUAD	C7 →	-1.582	-0.466	<.001	<.001	3	4
OV	WDR12 →	-0.508	-0.320	.002	.001	3	4
UCEC	OSR1 →	-0.904	-0.405	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,247 associations by consensus.

CISD2 vs TNXB — UCEC

Explore this scatter interactively →