CIAO3

Across TCGA patient cohorts, CIAO3 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,692 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CIAO3-associated proteins across cancer lineages are STUB1, STUB1_S273, and DCTPP1. Each is linked with CIAO3 in more than 6 cancer types. Because this analysis shows association rather than direction, both CIAO3-to-partner and partner-to-CIAO3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CIAO3 versus STUB1 in OV, with a Pearson correlation of 0.63.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CIAO3→partner) and Y-score (partner→CIAO3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	STUB1 →	+0.512	+0.497	<.001	<.001	3	7
PDAC	STUB1_S273 →	+0.927	+0.281	.002	.009	3	7
OV	DCTPP1 →	+0.734	+0.624	<.001	<.001	3	6
UCEC	JPT2 →	+0.407	+0.587	<.001	<.001	3	6
OV	STUB1_S19 →	+0.582	+0.399	<.001	<.001	3	5
GBM	CREBBP →	+0.283	+0.289	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,692 associations by consensus.

CIAO3 vs STUB1 — OV

Explore this scatter interactively →