CIAO3

Across TCGA cell cohorts, CIAO3 RNA expression is significantly associated with the RNA expression of many other genes, with 12,922 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible CIAO3-associated genes across cancer lineages are RHOT2, SRRM2, and RAB40C. Each is linked with CIAO3 in more than 19 cancer types. Because this analysis shows association rather than direction, both CIAO3-to-partner and partner-to-CIAO3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CIAO3 versus RHOT2 in UPPER_AERODIGESTIVE_TRACT, with a Pearson correlation of 0.83.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CIAO3→partner) and Y-score (partner→CIAO3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	RHOT2 →	+1.244	+1.108	<.001	<.001	3	20
OESOPHAGUS	SRRM2 →	+1.397	+1.422	<.001	<.001	3	19
OESOPHAGUS	RAB40C →	+1.553	+1.402	<.001	<.001	3	19
BONE	TSC2 →	+1.286	+0.651	<.001	<.001	3	19
OESOPHAGUS	PIGQ →	+1.493	+1.298	<.001	<.001	3	19
BREAST	NUBP2 →	+0.895	+0.964	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,922 associations by consensus.

CIAO3 vs RHOT2 — UPPER_AERODIGESTIVE_TRACT

Explore this scatter interactively →