CHRAC1

Across TCGA patient cohorts, CHRAC1 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CHRAC1-associated genes across cancer lineages are RNA5SP534, RNU7-95P, and MIR4673. Each is linked with CHRAC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CHRAC1-to-partner and partner-to-CHRAC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP534 grouped by CHRAC1-low versus CHRAC1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHRAC1→partner) and Y-score (partner→CHRAC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP534 →	+1.211	+5.242	<.001	.007	3	1
HNSC	RNU7-95P →	+0.338	+7.954	<.001	.008	3	1
UCEC	MIR4673 →	+1.109	+4.982	<.001	.009	3	1
UCEC	RNU6-1020P →	+0.575	+5.420	<.001	.005	3	1
UCEC	RNU6-1318P →	+0.945	+5.358	<.001	.006	3	1
UCEC	SNORA36C →	+0.615	+5.551	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

RNA5SP534 by CHRAC1 expression — UCEC

Explore this box plot interactively →