CHN1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CHN1 protein abundance is significantly associated with the RNA expression of many other genes, with 7,682 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CHN1-associated genes across cancer lineages are LDB2, CDH5, and C2CD4B. Each is linked with CHN1 in more than 3 cancer types. Because this analysis shows association rather than direction, both CHN1-to-partner and partner-to-CHN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHN1 versus LDB2 in CCRCC, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHN1→partner) and Y-score (partner→CHN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CCRCCLDB2 →+1.191+0.588.007<.00134
CCRCCCDH5 →+0.951+0.530.007.00134
LUADC2CD4B →+1.134+0.435<.001<.00134
LSCCTMOD2 →+0.656+0.385<.001<.00134
LSCCFAM107A →+1.142+0.400<.001<.00134
CCRCCCRACDL →+0.683+0.428<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 7,682 associations by consensus.

CHN1 vs LDB2 — CCRCC

Per-sample scatter of CHN1 vs LDB2 in CCRCC (Pearson r = 0.49).

Explore this scatter interactively →

Exploration