CHMP4C

Across TCGA patient cohorts, CHMP4C protein abundance is significantly associated with the RNA expression of many other genes, with 5,168 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CHMP4C-associated genes across cancer lineages are CXCL12, CHRAC1, and AHNAK. Each is linked with CHMP4C in more than 3 cancer types. Because this analysis shows association rather than direction, both CHMP4C-to-partner and partner-to-CHMP4C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHMP4C versus CXCL12 in HNSC, with a Pearson correlation of -0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHMP4C→partner) and Y-score (partner→CHMP4C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CXCL12 →	-0.916	-0.452	<.001	<.001	3	4
BRCA	CHRAC1 →	+0.372	+0.313	<.001	.005	3	3
LSCC	AHNAK →	+0.498	+0.424	<.001	<.001	3	3
LUAD	CPNE3 →	+0.483	+0.373	<.001	<.001	3	3
CCRCC	CPXM1 →	-0.732	-0.266	<.001	<.001	3	3
UCEC	CCDC80 →	-1.332	-0.369	<.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,168 associations by consensus.

CHMP4C vs CXCL12 — HNSC

Explore this scatter interactively →