CHMP4B

Across TCGA patient cohorts, CHMP4B protein abundance is significantly associated with the RNA expression of many other genes, with 12,767 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CHMP4B-associated genes across cancer lineages are GSS, TTPAL, and STAU1. Each is linked with CHMP4B in more than 4 cancer types. Because this analysis shows association rather than direction, both CHMP4B-to-partner and partner-to-CHMP4B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHMP4B versus GSS in BRCA, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHMP4B→partner) and Y-score (partner→CHMP4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	GSS →	+0.423	+0.236	.001	<.001	3	5
LUAD	TTPAL →	+0.471	+0.241	<.001	<.001	3	5
COAD	STAU1 →	+0.518	+0.339	<.001	<.001	3	5
COAD	DYNLRB1 →	+0.600	+0.300	<.001	<.001	3	5
COAD	BCL2L1 →	+0.552	+0.280	<.001	<.001	3	5
COAD	ITCH →	+0.378	+0.265	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,767 associations by consensus.

CHMP4B vs GSS — BRCA

Explore this scatter interactively →