CHIA

Across TCGA patient cohorts, CHIA RNA expression is significantly associated with the protein abundance of many other proteins, with 12,871 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CHIA-associated proteins across cancer lineages are NUP35_T273, LAPTM4A, and CEP164_S359. Each is linked with CHIA in more than 2 cancer types. Because this analysis shows association rather than direction, both CHIA-to-partner and partner-to-CHIA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHIA versus NUP35_T273 in LSCC, with a Pearson correlation of -0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CHIA→partner) and Y-score (partner→CHIA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	NUP35_T273 →	-0.377	-0.477	<.001	<.001	3	3
LUAD	LAPTM4A →	+0.888	+0.811	<.001	<.001	3	3
LUAD	CEP164_S359 →	+0.350	+0.798	.002	<.001	3	3
OV	ABCD3 →	+0.345	+0.113	.002	<.001	3	3
LUAD	EIF4B_S93 →	-0.565	-0.846	<.001	<.001	3	3
LUAD	FASN_S1411 →	-0.642	-0.903	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,871 associations by consensus.

CHIA vs NUP35_T273 — LSCC

Explore this scatter interactively →