CHI3L2

Across TCGA patient cohorts, CHI3L2 protein abundance is significantly associated with the protein abundance of many other proteins, with 17,660 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CHI3L2-associated proteins across cancer lineages are RFC1, S100A8, and S100A9. Each is linked with CHI3L2 in more than 3 cancer types. Because this analysis shows association rather than direction, both CHI3L2-to-partner and partner-to-CHI3L2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHI3L2 versus RFC1 in LSCC, with a Pearson correlation of -0.60.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CHI3L2→partner) and Y-score (partner→CHI3L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RFC1 →	-0.736	-1.393	.001	.001	3	3
HNSC	S100A8 →	+1.625	+0.969	.001	.008	3	3
HNSC	S100A9 →	+1.482	+1.184	.001	<.001	3	3
GBM	UBTF →	-0.453	-1.112	<.001	<.001	3	3
LSCC	USP39 →	-0.902	-1.505	<.001	<.001	3	3
LSCC	WRNIP1 →	-0.992	-1.170	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,660 associations by consensus.

CHI3L2 vs RFC1 — LSCC

Explore this scatter interactively →