CHD3

Across TCGA cell cohorts, CHD3 RNA expression is significantly associated with the RNA expression of many other genes, with 11,546 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CHD3-associated genes across cancer lineages are POLR2A, ANKFY1, and TP53BP1. Each is linked with CHD3 in more than 16 cancer types. Because this analysis shows association rather than direction, both CHD3-to-partner and partner-to-CHD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHD3 versus POLR2A in UPPER_AERODIGESTIVE_TRACT, with a Pearson correlation of 0.63.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHD3→partner) and Y-score (partner→CHD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	POLR2A →	+1.394	+1.447	<.001	<.001	3	16
OESOPHAGUS	ANKFY1 →	+1.167	+1.356	.002	.007	2	17
UPPER_AERODIGESTIVE_TRACT	TP53BP1 →	+1.050	+0.868	<.001	<.001	3	16
BLOOD_Lymphoma	ZZEF1 →	+1.075	+0.949	<.001	<.001	3	15
LARGE_INTESTINE	PELP1 →	+1.062	+1.525	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	NCBP3 →	+1.220	+1.495	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,546 associations by consensus.

CHD3 vs POLR2A — UPPER_AERODIGESTIVE_TRACT

Explore this scatter interactively →