CHCHD2

Across TCGA patient cohorts, CHCHD2 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,048 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CHCHD2-associated proteins across cancer lineages are NUDCD3, MCM7, and CDKN1B. Each is linked with CHCHD2 in more than 6 cancer types. Because this analysis shows association rather than direction, both CHCHD2-to-partner and partner-to-CHCHD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHCHD2 versus NUDCD3 in GBM, with a Pearson correlation of 0.12.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CHCHD2→partner) and Y-score (partner→CHCHD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	NUDCD3 →	+0.339	+0.565	<.001	.004	2	7
LUAD	MCM7 →	+0.549	+0.427	<.001	<.001	3	5
LSCC	CDKN1B →	-0.465	-0.760	<.001	<.001	3	5
LSCC	CSE1L →	+0.332	+0.381	<.001	<.001	3	5
COAD	EIF4H →	+0.263	+0.520	<.001	<.001	3	5
LUAD	HSPA14 →	+0.276	+0.480	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,048 associations by consensus.

CHCHD2 vs NUDCD3 — GBM

Explore this scatter interactively →