CHAF1B

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CHAF1B protein abundance is significantly associated with the RNA expression of many other genes, with 17,944 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CHAF1B-associated genes across cancer lineages are CENPM, CDKN3, and GINS1. Each is linked with CHAF1B in more than 8 cancer types. Because this analysis shows association rather than direction, both CHAF1B-to-partner and partner-to-CHAF1B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHAF1B versus CENPM in GBM, with a Pearson correlation of 0.79.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHAF1B→partner) and Y-score (partner→CHAF1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMCENPM →+1.269+0.763<.001<.00139
LUADCDKN3 →+1.201+0.467<.001<.00139
LUADGINS1 →+1.274+0.573<.001<.00139
LUADCENPI →+1.257+0.596<.001<.00139
COADMCM4 →+1.083+0.810<.001<.00139
LSCCEZH2 →+1.056+0.671<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 17,944 associations by consensus.

CHAF1B vs CENPM — GBM

Per-sample scatter of CHAF1B vs CENPM in GBM (Pearson r = 0.79).

Explore this scatter interactively →

Exploration