CH25H

Across TCGA cell cohorts, CH25H RNA expression is significantly associated with the go_rna of many other GO terms, with 1,225 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible CH25H-associated GO terms across cancer lineages are Regulation of cytokine-mediated signaling pathway, Adrenal gland development, and Antigen processing and presentation of exogenous peptide antigen via MHC class Ib. Each is linked with CH25H in more than 6 cancer types. Because this analysis shows association rather than direction, both CH25H-to-partner and partner-to-CH25H results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cytokine-mediated signaling pathway grouped by CH25H-low versus CH25H-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CH25H→partner) and Y-score (partner→CH25H) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Regulation of cytokine-mediated signaling pathway →	+0.056	+0.668	<.001	<.001	3	7
LUNG_NSCLC_LUAD	Adrenal gland development →	+0.152	+0.626	<.001	<.001	3	7
SOFT_TISSUE	Antigen processing and presentation of exogenous peptide antigen via MHC class Ib →	+0.157	+0.460	.009	.009	2	7
SKIN	Apoptotic signaling pathway →	+0.029	+0.350	.002	.006	3	6
SKIN	T cell differentiation in thymus →	+0.053	+0.452	.009	.006	3	6
CNS	Positive regulation of focal adhesion assembly →	+0.098	+1.211	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,225 associations by consensus.

Regulation of cytokine-mediated signaling pathway by CH25H expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →