CH25H

Across TCGA cell cohorts, CH25H mutation is significantly associated with the mutation status of many other genes, with 370 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CH25H-associated genes across cancer lineages are ARNTL2, NPFFR2, and SYP. Each is linked with CH25H in more than 1 cancer types. Because this analysis shows association rather than direction, both CH25H-to-partner and partner-to-CH25H results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ARNTL2 grouped by CH25H-low versus CH25H-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CH25H→partner) and Y-score (partner→CH25H) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ARNTL2 →	+4.523	+5.087	.006	.006	1	2
LARGE_INTESTINE	NPFFR2 →	+4.523	+5.087	.006	.006	1	2
LARGE_INTESTINE	SYP →	+4.523	+5.087	.006	.006	1	2
LARGE_INTESTINE	SLC7A6OS →	+5.523	+5.523	.003	.003	1	2
LARGE_INTESTINE	LRRC59 →	+4.523	+5.087	.006	.006	1	2
LARGE_INTESTINE	CAAP1 →	+4.523	+5.087	.006	.006	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 370 associations by consensus.

ARNTL2 by CH25H expression — LARGE_INTESTINE

Explore this box plot interactively →